YK-11 Powder (Myostine)

A. Introduction

YK-11 (Myostine) is one of the most complex compounds in the SARM category, distinguished by its unique steroidal backbone. Unlike non-steroidal SARMs, YK-11 is frequently studied for its dual-action potential as both a partial androgen receptor agonist and a potential myostatin inhibitor via the induction of follistatin. Our YK-11 powder is synthesized to meet the precise requirements of high-level genomic and proteomic research.

B. Scientific Overview

Chemically identified as (17α,20E)-17,20-[(1-methoxyethylidene)bis(oxy)]-3-oxo-19-norpregna-4,20-diene-21-carboxylic acid methyl ester ($C_{25}H_{34}O_{6}$), YK-11 is a derivative of ethisterone. In in-vitro laboratory settings, researchers investigate how YK-11 modulates the expression of myogenic regulatory factors. Specifically, it is utilized to study the up-regulation of Follistatin, a glycoprotein that acts as an antagonist to Myostatin.

C. Product Specifications

• Form: Crystalline powder
• Chemical Class: Steroidal SARM / Myostatin Inhibitor Analogue
• Molecular Formula: $C_{25}H_{34}O_{6}$
• Molecular Weight: 430.54 g/mol
• Purity: ≥99% (HPLC/NMR Verified)
• Solubility: Soluble in DMSO and Ethanol
• Storage: Store in a cool, dry place (15°C to 25°C) in an airtight container; protect from light and moisture.

D. Laboratory Use Context

This pure powder format is provided exclusively for in-vitro research and analytical testing. It is a primary reagent for:

• Investigating androgen receptor (AR) transcriptional activity.
• Studying the molecular pathways of Follistatin induction in muscle cell cultures.
• Calibrating LC-MS and GC-MS equipment for SARM screening.
• In-vitro toxicity and stability profiling in synthetic biological matrices.

E. Quality Testing

• HPLC Verification: Every batch is verified for chemical purity and the absence of related steroidal impurities.
• Structural Identity: Mass Spectrometry (MS) and Proton NMR ensure the correct identification of the complex methoxyethylidene group.
• Batch Consistency: Rigorous manufacturing standards ensure that every unit provides reproducible results for long-term longitudinal studies.
• COA: Detailed Certificates of Analysis are provided for all institutional research requirements.

F. Shipping Handling

Our YK-11 powder is dispatched in professional, vacuum-sealed, and UV-protected packaging to maintain the stability of the steroidal nucleus during transit. We provide reliable, discreet worldwide shipping to research facilities and commercial laboratories, ensuring all necessary documentation is included for compliant logistics.

G. Compliance Disclaimer (CLEAR PROMINENT)

FOR RESEARCH USE ONLY. NOT FOR HUMAN CONSUMPTION. This product is a research chemical and is strictly for in-vitro laboratory applications and analytical testing. It is not intended for diagnostic or therapeutic use in humans or animals. No instructions for administration or medical dosages are provided. The purchaser assumes all responsibility for compliance with local and international regulations regarding the acquisition and handling of this substance.